Pain at the injection propofol can be minimized by the simultaneous administration of lidocaine or infusion into a large vein of the forearm or antecubital fossa When combined administration rarely lidocaine were observed following adverse effects: dizziness, vomiting, drowsiness, convulsions, bradycardia, cardiac arrhythmia and shock. rare: . Postoperative trenbolone hex feverVery rare: described isolated cases of severe adverse effects in the form of a complex of symptoms: rhabdomyolysis, metabolic acidosis, hyperkalemia, and cardiac failure, sometimes with fatal consequences. In most cases, these symptoms are observed in ICU patients who received doses higher.
Overdose can lead to inhibition of the cardiovascular and respiratory systems. During the suppression of the respiratory system is carried out artificial respiration. In case of violation the head end of the bed should be deleted cardiovascular function and start administering plasma expanders and / or vasopressor agents.
Interaction with other drugs
May be used in conjunction with other drugs commonly used for sedation, inhalation anesthesia, analgesics, muscle relaxants or local anesthetic. Some centrally acting drugs may exert a suppressive effect on the cardiovascular system and respiratory system and can enhance the effect of propofol. If general anesthesia combined with local, can be used a lower dose.
Combined use of benzodiazepines, m-holinoblokatorov or – anesthetic sometimes causes elongation of anesthesia and reduced respiratory rate.
After premedication with narcotic analgesics may increase iprodlenie sedative propofol, as well as an increase in the frequency and duration apnea. It should be appreciated that the use with both premedication with inhaled anesthetics or analgesics, may potentiate anesthesia and side effects to the cardiovascular system. Interactions with them drugs that suppress the central nervous system, for example, alcohol, general anesthetics, narcotic analgesics leads to severe manifestations of their sedative effects.
When combined with administered parenterally administered drugs, depressing the central nervous system, possibly heavy respiratory depression and cardiac activity.
After administration of fentanyl possible transient increase in blood concentration of propofol, accompanied by an increase in the probability of sleep apnea.
After the introduction of suxamethonium or neostigmine may occur bradycardia and heart failure.
in patients receiving cyclosporine, described cases of leukoencephalopathy with the introduction of fat emulsions, such trenbolone hex special instructions
Did not reduce vagal tone, and its use in some cases accompanied by bradycardia (sometimes severe) and asystole.
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Prior to induction or maintenance of general anesthesia during should consider intravenous m- anticholinergics, especially in cases presumably enhanced vagal tone, or when applying in conjunction with other agents capable of causing bradycardia.
For ease pain at the injection site during induction of general anesthesia before administration of the emulsion preparation can introduce lidocaine. In the application of lidocaine should be aware that it can not be used in patients with hereditary porphyria.
Trenbolone hexmay be used only physicians trained in anesthesia or intensive care.
Should not be administered by personnel conducting diagnostic or surgical manipulation.
Efficacy and safety of sedation of children under the age of 16 years have not been studied. In case of unauthorized use of the drug for (background) sedation of children under the age of 16 reported cases of serious pobochngh effects, including death, although a causal relationship has not been established in these cases. how much to inject for weight loss
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